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There are several matches for 'alpha-ketoglutarate dehydrogenase'.
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1846 matches
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organism
protein
1)
Homo sapiens
OGDH - 2-oxoglutarate
dehydrogenase
, mitochondrial; 2-oxoglutarate
dehydrogenase
(E1) component of the 2- oxoglutarate
dehydrogenase
complex, which mediates the decarboxylation of
alpha
-
ketoglutarate
. The 2-oxoglutarate
dehydrogenase
complex catalyzes the overall conversion of 2- oxoglutarate to succinyl-CoA and CO(2). The 2- oxoglutarate
dehydrogenase
complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate
dehydrogenase
complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-C [...]
[a.k.a. OGDH-207, ENST00000459672.5, BC004964,
Alpha-ketoglutarate dehydrogenase
]
2)
Mus musculus
Ogdh - 2-oxoglutarate
dehydrogenase
, mitochondrial; 2-oxoglutarate
dehydrogenase
(E1) component of the 2- oxoglutarate
dehydrogenase
complex, which mediates the decarboxylation of
alpha
-
ketoglutarate
. The 2-oxoglutarate
dehydrogenase
complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate
dehydrogenase
complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate
dehydrogenase
complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl- Co [...]
[a.k.a. UPI00004704CC, NM_010956, Z4YJV4,
alpha-ketoglutarate dehydrogenase
,
Alpha-ketoglutarate dehydrogenase
, ...]
3)
Caenorhabditis elegans
ogdh-1 - 2-oxoglutarate dehydrogenase, mitochondrial; The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity).
[a.k.a. T22B11.5a, CDH93321, Ogdh-1,
Alpha-ketoglutarate dehydrogenase
]
4)
Escherichia coli K12
sucA - 2-oxoglutarate decarboxylase, thiamine triphosphate-binding; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).
[a.k.a. b0726, AAC73820.1, eco:b0726,
Alpha-ketoglutarate dehydrogenase
]
5)
Saccharomyces cerevisiae
KGD1 - 2-oxoglutarate
dehydrogenase
, mitochondrial; Subunit of the mitochondrial
alpha
-
ketoglutarate
dehydrogenase
complex; catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of
alpha
-
ketoglutarate
to form succinyl-CoA.
[a.k.a. YIL125W, CAA86867.1, YIL125W_mRNA,
Alpha-ketoglutarate dehydrogenase
]
6)
Homo sapiens
DLD - Dihydrolipoyl
dehydrogenase
, mitochondrial; Lipoamide
dehydrogenase
is a component of the glycine cleavage system as well as an E3 component of three
alpha
-ketoacid
dehydrogenase
complexes (pyruvate-,
alpha
-
ketoglutarate
-, and branched- chain amino acid-
dehydrogenase
complex). The 2-oxoglutarate
dehydrogenase
complex is mainly active in the mitochondrion. A fraction of the 2- oxoglutarate
dehydrogenase
complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KA [...]
[a.k.a. ENSP00000387542, E3, ENST00000639772]
7)
Homo sapiens
GLUD1 - Glutamate
dehydrogenase
1, mitochondrial; Mitochondrial glutamate
dehydrogenase
that converts L- glutamate into
alpha
-
ketoglutarate
. Plays a key role in glutamine anaplerosis by producing
alpha
-
ketoglutarate
, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate (By similarity).
[a.k.a. X66300, HPA042492, X07674]
8)
Homo sapiens
OGDHL - 2-oxoglutarate
dehydrogenase
-like, mitochondrial; Oxoglutarate
dehydrogenase
L; Belongs to the
alpha
-
ketoglutarate
dehydrogenase
family.
[a.k.a. ENST00000471460.1, HGNC:25590, ENST00000496884.1]
9)
Homo sapiens
IDH3A - Isocitrate
dehydrogenase
[NAD] subunit
alpha
, mitochondrial; Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into
alpha
-
ketoglutarate
. The heterodimer composed of the
alpha
(IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the
alpha
(IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
[a.k.a. IDH3A-221, 6KDY, 5YVT]
10)
Homo sapiens
IDH3G - Isocitrate
dehydrogenase
[NAD] subunit gamma, mitochondrial; Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into
alpha
-
ketoglutarate
. The heterodimer composed of the
alpha
(IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the
alpha
(IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
[a.k.a. 5YVT, CH471172, hsa:3421]
11)
Homo sapiens
IDH3B - Isocitrate
dehydrogenase
[NAD] subunit beta, mitochondrial; Plays a structural role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into
alpha
-
ketoglutarate
. The heterodimer composed of the
alpha
(IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the
alpha
(IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
[a.k.a. 6KDY, ENST00000344871, D3DVX2]
12)
Mus musculus
Dld - Dihydrolipoyl
dehydrogenase
, mitochondrial; Lipoamide
dehydrogenase
is a component of the glycine cleavage system as well as an E3 component of three
alpha
-ketoacid
dehydrogenase
complexes (pyruvate-,
alpha
-
ketoglutarate
-, and branched- chain amino acid-
dehydrogenase
complex) (By similarity). The 2- oxoglutarate
dehydrogenase
complex is mainly active in the mitochondrion (By similarity). A fraction of the 2-oxoglutarate
dehydrogenase
complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA t [...]
[a.k.a. 13382, Dld-201, Dld-204]
13)
Mus musculus
Glud1 - Glutamate
dehydrogenase
1, mitochondrial; Mitochondrial glutamate
dehydrogenase
that converts L- glutamate into
alpha
-
ketoglutarate
. Plays a key role in glutamine anaplerosis by producing
alpha
-
ketoglutarate
, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate; Belongs to the Glu/Leu/Phe/Val
dehydrogenases
family.
[a.k.a. 14661, NM_008133.4, NP_032159]
14)
Mus musculus
Idh3a - Isocitrate
dehydrogenase
[NAD] subunit
alpha
, mitochondrial; Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into
alpha
-
ketoglutarate
. The heterodimer composed of the
alpha
(IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the
alpha
(IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
[a.k.a. AK153459, Idh3a-202, AK168049]
15)
Mus musculus
4933405O20Rik - Probable isocitrate
dehydrogenase
[NAD] gamma 2, mitochondrial; Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into
alpha
-
ketoglutarate
. The heterodimer composed of the
alpha
(IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the
alpha
(IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
[a.k.a. 243996, Q8BPC6, NM_172901]
16)
Mus musculus
Idh3g - Isocitrate
dehydrogenase
[NAD] subunit gamma 1, mitochondrial; Regulatory subunit which plays a role in the allosteric regulation of the enzyme catalyzing the decarboxylation of isocitrate (ICT) into
alpha
-
ketoglutarate
. The heterodimer composed of the
alpha
(IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the
alpha
(IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers.
[a.k.a. Idh3g-207, ENSMUST00000052761, AAI19171.1]
17)
Saccharomyces cerevisiae
SER3 - D-3-phosphoglycerate
dehydrogenase
1; 3-phosphoglycerate
dehydrogenase
and
alpha
-
ketoglutarate
reductase; 3PG
dehydrogenase
that catalyzes the first step in serine and glycine biosynthesis; also functions as an
alpha
-
ketoglutarate
reductase, converting
alpha
-
ketoglutarate
to D-2-hydroxyglutarate (D-2HG); localizes to the cytoplasm; SER3 has a paralog, SER33, that arose from the whole genome duplication.
[a.k.a. YER081W, Phosphoglycerate dehydrogenase SER3, 1.1.1.399]
18)
Saccharomyces cerevisiae
SER33 - D-3-phosphoglycerate
dehydrogenase
2; 3-phosphoglycerate
dehydrogenase
and
alpha
-
ketoglutarate
reductase; 3PG
dehydrogenase
that catalyzes the first step in serine and glycine biosynthesis; also functions as an
alpha
-
ketoglutarate
reductase, converting
alpha
-
ketoglutarate
to D-2-hydroxyglutarate (D-2HG); localizes to the cytoplasm; SER33 has a paralog, SER3, that arose from the whole genome duplication.
[a.k.a. YIL074C, NM_001179424.1, 1.1.1.399]
19)
Saccharomyces cerevisiae
GDH3 - NADP(+)-dependent glutamate
dehydrogenase
; synthesizes glutamate from ammonia and
alpha
-
ketoglutarate
; rate of
alpha
-
ketoglutarate
utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources; GDH3 has a paralog, GDH1, that arose from the whole genome duplication; Belongs to the Glu/Leu/Phe/Val
dehydrogenases
family.
[a.k.a. YAL062W, NP_009339.1, 1.4.1.4]
20)
Saccharomyces cerevisiae
GDH1 - NADP(+)-dependent glutamate
dehydrogenase
; synthesizes glutamate from ammonia and
alpha
-
ketoglutarate
; rate of
alpha
-
ketoglutarate
utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources; GDH1 has a paralog, GDH3, that arose from the whole genome duplication.
[a.k.a. YOR375C, 1.4.1.4, NM_001183795.3]
1846 matches
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